For the fourth time in the past six months, the Creighton University Mid-America Business Conditions Index, a leading economic indicator for the nine-state region stretching from Minnesota to Arkansas, moved below growth neutral. The, which index ranges between 0 and 100 with 50.0 representing growth neutral, fell to 47.6, its lowest reading for 2025, and down from 49.5 in November. The regional manufacturing sector shed jobs for the ninth straight month.

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